Drugdelivery相关论文
Osteoarthritis is characterized by lubrication failure of the articular cartilage and severe inflammation of the joint c......
Although multifarious tumor-targeting modifications of nanoparticulate systems have been at-tempted in joint efforts by ......
The use of small interfering RNAs(siRNAs)has been under investigation for the treatment of several unmet medical needs,i......
Self-assembled metal-organic frameworks nanocrystals synthesis and application for plumbagin drug de
Metal-organic frameworks (MOFs) have recently allured a variety of concern in the fields of nanotech-nology.However,expl......
Smart supramolecular vesicles based on glutathione-reactive pillar[6]arene and acid-labile prodrug:D
Glutathione thiol-reactive pillar[6]arene (TWP6) is designed and synthesized as the first example of reducing agent-reac......
Emulsions are liquid-liquid dispersions with one liquid phase dispersed in the other liquid phase as small droplets.Nano......
Platelets contribute a major role in hemostasis by clumping and coagulation at the site of blood vessel injuries.In ligh......
Based on a recent report concerning endogenous agents (i.e., pyridoxal phosphate, adenosine triphosphate, adenosine mono......
Drug delivery systems (DDS) are used to deliver therapeutic drugs to improve selectivity and reduce side effects. With t......
The gastrointestinal tract is an eight-meter-long pathway that includes various organs,which runs from the mouth to the ......
Regarding the increasing number of cancer patients,the global burden of this disease is continuing to grow.Despite a con......
Intelligent self-assembly prodrug micelles loading doxorubicin in response to tumor microenvironment
Compared with physical drug-loaded nanocarriers,polymeric prodrug micelles have many advantages such as high drug loadin......
A pH Self-Monitoring Heterogeneous Multicompartmental Proteinosome with Spatiotemporal Regulation of
Inspired by the intricate eukaryotic cell structure,the spontaneously assembling multicompartments capable of spatiotemp......
目的:探讨牛乳-紫草素纳米载药体系对肝癌细胞的杀伤作用。方法:采用实验研究方法。采用差速离心法分离出牛乳外泌体，制备牛乳-紫草......
Infectious diseases caused by bacteria are a global threat to the human health.Here,we propose a solvent “irrigation” ......
Nanomedicine-mediated ubiquitination inhibition boosts antitumor immune response via activation of d
Tumor immunotherapy as a promising method for tumor treatment received tremendous attention.However,the problem of low c......
Hollow mesoporous polyaniline nanoparticles with high drug payload and robust photothermal capabilit
In recent years,synergistic chemo-photothermal therapy has revealed promising potential in treatments against various ki......
Polydopamine functionalized mesoporous silica as ROS-sensitive drug delivery vehicles for periodonti
Periodontitis is recognized as the major cause of tooth loss in adults,posing an adverse impact on systemic health.In pe......
Many emerging strategies in chemo-,gene-,and immunotherapy require the accumulation of reagents in the cell nucleus.Howe......
Schiff-base silver nanocomplexes formation on natural biopolymer coated mesoporous silica contribute
Infectious microbes that spread easily in healthcare facilities remain as the severe threat for the public health,especi......
Lung diseases,including COVID-19 and lung cancers,is a huge threat to human health.However,for the treatment and diagnos......
In recent years,the hydrogel-based tissue adhesives have been extensively investigated for their excellent biocompatibil......
Monoclonal Antibody-conjugated Polyphosphoester-hyd-DOX Prodrug Nanoparticles for Targeted Chemother
In order to overcome the limitation of traditional active nano-therapeutic drugs on tumor targeting effciency which cann......
Invasive fungal infections(IFIs)represent a growing public concern for clinicians to manage in many medical settings,wit......
Amorphous solid dispersions(ASDs)are popular for enhancing the solubility and bioavailability of poorly water-soluble dr......
Orally administered drug entities have to survive the harsh gastrointestinal environment,penetrate the enteric epithelia......
Proteases have a fundamental role in maintaining physiological homeostasis,but their dysre-gulation results in severe ac......
The administration of nanoparticles(NPs)first faces the challenges of evading renal filtration and clearance of reticulo......
Immunotherapy is a rapidly developing area of cancer treatment due to its higher specificity and potential for greater e......
...
Self-assembly between soft and nano materials allows the generation of new multiplexed drug delivery vehicles with good ......
Controllable synthesis of multifunctional Gd-based upconversion luminescence nanomaterials for biome
Upconversion nanoparticles (UCNPs), as a promising new class of biological fluorescent probes, have recently received co......
Gadolinium-based fluorescent nanoparticles are ideal building blocks for construction of multifunctional theranostics ag......
Assembly of Fe3O4 Nanoparticles onto PEG-functionalized Graphene Oxide for Efficient Magnetic Imagin
Among various all-in-one theranostic NPs,Fe3O4 NPs have merged as one of most appealing candidates.Fe3O4 nanoparticles(N......
Superior Intratumoral Penetration of Paclitaxel Nanodots Strengthens Tumor Restriction and Metastasi
Recently discovered intratumoral diffusion resistance,together with poor solubility and non-targeted distribution of che......
Chemotherapy seeks to minimize tumor progression and increase patient survival.However,the main problem is to find a bal......
Biodegradable PLA-Mediated Sustainable Release Nanocarrier for Target Drug Delivery and Mitigating t
Till now,chemotherapy is still the standard treatment after cancer surgical resection.However,the severe side-effects an......
There is a growing effort in the scientific community to design and fabricate self-propelled artificial nanomotors becau......
Complementary Drug Delivery Systems to Overcome Biological Barriers that Characterize Systemic Treat
Uncontrolled cellular proliferation and chronic inflammatory state are two main features of cancer pathology.Tumors surv......
Self-Assembled Plasmonic Vesicles of SERS-Encoded Amphiphilic Gold Nanoparticles for Cancer Cell Tar
We report the development of bioconjugated plasmonic vesicles assembled from SERS-encoded amphiphilic gold nanoparticles......
A Photothermally Triggered and Glutathione-Responsive Drug Delivery Platform through DNA/Copper Sulf
The biomedical applications of nanotechnology have attracted much attention in recent years.One of them is using nanopar......
A novel biodegradable amphiphilic copolymer based on chitosan, poly(lactide) and 1,2-dipalmitoyl-sn-glycero-3-phosphoeth......
Amphiphilic Poly(2-hydroxyethyl methacrylate)-g-poly(lactide)-1,2-dipalmitoyl-sn-glycero-3-phosphoet
In this paper, a novel doxorubicin (DOX)-loaded amphiphilic poly(2-hydroxyethylmcthacrylate)-gpoly(lactide)-1,2-dipalmit......
One of challenge for cancer therapy is efficient delivery of anticancer agents into tumor sites to increase the efficien......
This paper takes on tumor cells in targeting dual functions of diagnosis and treatment in one of the FePt/GO-AS1411 nano......
The physical properties, such as shape, size,mechanical properties, surface texture and compartmentalization, profoundly......
Carbon quantum dots (C-dots) are usually derived from oxidization of carbon precursors, including candle soot, carbon na......
The body is composed of several biophysical barriers that regulate the exchange, trafficking, and clearance of foreign m......
pH-Responsive hydroxyapatite and hyaluronic acid modified mesoporous silica nanoparticles for target
In recent decades,various kinds of nanomaterials have been widely investigated as potential therapeutic agents for cance......
